Of Mice And Men Inoculating Mice With Viruses

In an experiment involving the ever-unfortunate mice, the following steps occurred:

  • Mice inoculated with influenza virus
  • Th17 cells activated and migrate to respiratory and gastrointestinal systems
    • Both respiratory and gastrointestinal tracts have mucosa, so they are similar in a way
  • Th17 cells produce cytokines IL-17A and IFN-γ
    • These cytokines mess with intestinal bacteria
    • Results in less Lacto-, more Entero-
  • Intestinal injury

References

  1. Racaniello, V. (2014). How influenza virus infection might lead to gastrointestinal symptoms. [online] virology blog. Available at: http://www.virology.ws/2014/12/10/how-influenza-virus-infection-might-lead-to-gastrointestinal-symptoms/ [Accessed 5 Feb. 2020].

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